Thermo Fisher Scientific OGDH Monoclonal Antibody (9F4BD5)

Applications

Western Blot (WB)

• Tested Dilution: 0.25 µg/mL

Immunocytochemistry (ICC/IF)

• Tested Dilution: 1.0 µg/mL

ELISA

• Tested Dilution: Assay-dependent

Product Specifications

Target Information

This gene encodes one subunit of the 2-oxoglutarate dehydrogenase complex. This complex catalyzes the overall conversion of 2-oxoglutarate (alpha-ketoglutarate) to succinyl-CoA and CO₂ during the Krebs cycle. The protein is located in the mitochondrial matrix and uses thiamine pyrophosphate as a cofactor. A congenital deficiency in 2-oxoglutarate dehydrogenase activity is believed to lead to hypotonia, metabolic acidosis, and hyperlactatemia.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.