Thermo Fisher Scientific IL23R Monoclonal Antibody (OTI5C4), TrueMAB
인간 IL23R 단백질(aa 57-355)에 특이적인 Mouse IgG2a 단클론 항체. Western blot에 최적화된 TrueMAB 포맷. 고순도 친화 크로마토그래피 정제, PBS/BSA/glycerol 버퍼에 보관. 염증성 질환 연구용으로 적합.
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Applications
- Western Blot (WB): Tested dilution 1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI5C4 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 57–355 of human IL23R produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
IL-23R is a 629 amino acid subunit of the receptor for cytokine IL23A/IL23, which pairs with IL12RB1 (IL12R beta 1) to mediate IL23A signaling. It associates constitutively with Janus kinase 2 (JAK2) and binds to STAT3 in a ligand-dependent manner. Alternative splicing produces six isoforms of IL-23R. IL-23R is implicated in psoriasis pathogenesis and is a potential therapeutic target for inflammatory bowel disease.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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배송/결제/교환/반품 안내
배송 정보
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