Thermo Fisher Scientific IL-13 Polyclonal Antibody
IL-13 단백질을 인식하는 Rabbit Polyclonal Antibody로, Western blot 및 IHC(P) 실험에 적합합니다. Human, Mouse, Rat 시료에 반응하며, 고순도의 Affinity chromatography 정제 항체입니다. PBS/glycerol buffer에 보관되며 -20°C에서 안정적으로 저장 가능합니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human IL13 (Accession P35225), corresponding to amino acid residues L9–A59 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2851976 |
Product Specific Information
This antibody detects endogenous levels of total IL-13.
Target Information
IL-13 is an immunoregulatory cytokine produced primarily by activated Th2 cells, involved in regulating inflammatory and immune responses. It down-regulates macrophage activity, inhibiting pro-inflammatory cytokine and chemokine production, and plays a role in allergen-induced asthma independent of IgE and eosinophils. IL-13 also influences B cell maturation, up-regulates CD23 and MHC class II expression, and promotes IgE isotype switching. Structurally, IL-13 is similar to IL-3, IL-4, IL-5, and GM-CSF. The IL-13 gene is located on chromosome 5q within a cytokine gene cluster alongside IL3, IL5, IL4, and CSF2.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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