Thermo Fisher Scientific PON1 Polyclonal Antibody
Goat 유래 PON1 폴리클로날 항체로 Western blot에 적합. 사람 단백질 반응성 확인됨. 합성 펩타이드(aa 313–325)를 면역원으로 사용. 0.5 mg/mL 농도의 액상 형태로 제공되며, -20°C에서 보관. 연구용으로만 사용 가능.
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Applications
- Western Blot (WB): 1–3 µg/mL
- Publications: N/A
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide sequence (EEPKVTQVYAEN) corresponding to internal amino acids 313–325 of PON1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Ammonium sulfate precipitation |
| Storage Buffer | TBS, pH 7.3, with 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_10985332 |
Product Specific Information
This antibody has been tested in Peptide ELISA with an antibody detection limit dilution of 1:2,000.
Target Information
The paraoxonase (PON) gene family in humans includes PON1, PON2, and PON3, located on chromosome 7q21.3–22.1.
PON1 is synthesized primarily in the liver and secreted into plasma, where it associates with high-density lipoproteins (HDL).
It hydrolyzes active metabolites of several organophosphorus insecticides (e.g., chlorpyrifos oxon, diazoxon) and nerve agents such as sarin, soman, and VX.
PON1 polymorphisms may contribute to neurodegeneration and are considered an independent risk factor for Parkinson’s disease.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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