Thermo Fisher Scientific PDGFRL Polyclonal Antibody
인간 PDGFRL 단백질을 인식하는 Rabbit Polyclonal Antibody. 면역세포화학(ICC/IF)에 적합하며, 항원 친화 크로마토그래피로 정제됨. 액상 형태로 제공되며, 단기 4°C, 장기 -20°C 보관 권장. 연구용으로만 사용 가능.
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Applications
- Immunocytochemistry (ICC/IF): 0.25–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant Human PDGFRL. Recombinant protein control fragment (Product #RP-106417) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.05 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2663332 |
Product Specific Information
Immunogen sequence:
RGFVYLQPHSE HQGVVYCRAE AGGRSQISVK YQLLYVAVPS GPPSTTILAS SNKVKSGDDI SVLCTVLGEP DVEVEFTWIF PGQKDERPVT IQDTWRLIHR GLGHTTRISQ SVITVEDFET IDAGYYICTA QNLQGQTTV
Highest antigen sequence identity to the following orthologs:
- Mouse: 93%
- Rat: 94%
Target Information
PDGFRL bears significant sequence similarity to the ligand binding domain of platelet-derived growth factor receptor beta.
Mutations in the PDGFRL gene, or deletion of a chromosomal segment containing this gene, are associated with sporadic hepatocellular carcinomas, colorectal cancers, and non-small cell lung cancers.
This suggests PDGFRL may function as a tumor suppressor.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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