Thermo Fisher Scientific CD104 Recombinant Mouse Monoclonal Antibody (5C2)
Recombinant mouse monoclonal antibody (clone 5C2) targeting human ITGB4 protein. Suitable for flow cytometry and ELISA. High purity via affinity chromatography. Supplied in PBS with glycerol for enhanced stability. For research use only.
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Thermo Fisher Scientific CD104 Recombinant Mouse Monoclonal Antibody (5C2)
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Flow Cytometry (Flow) | 1:20–1:500 |
| ELISA | Assay-dependent |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 5C2 |
| Immunogen | Recombinant Human ITGB4 protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.03% Proclin 300 |
| Storage Conditions | -20°C or -80°C if preferred |
| Shipping Conditions | Wet ice |
| RRID | AB_3092485 |
Target Information
Integrins are heterodimers composed of alpha and beta subunits that form noncovalently associated transmembrane glycoprotein receptors. Different combinations of alpha and beta polypeptides yield complexes with varying ligand-binding specificities. Integrins mediate cell-matrix and cell-cell adhesion and transduce signals regulating gene expression and cell growth.
The ITGB4 gene encodes the integrin beta 4 subunit, a receptor for laminins. This subunit typically associates with the alpha 6 subunit and plays a key role in the biology of invasive carcinoma. Mutations in ITGB4 are linked to epidermolysis bullosa with pyloric atresia. Multiple alternatively spliced transcript variants encoding distinct isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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