Thermo Fisher Scientific ZDHHC18 Polyclonal Antibody
ZDHHC18 단백질을 인식하는 Thermo Fisher Scientific의 토끼 폴리클로날 항체로, IHC(P) 및 ICC/IF에 사용 가능. 인간 시료 반응성, 항원 친화 크로마토그래피 정제, 0.3 mg/mL 농도, 연구용 전용.
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Thermo Fisher Scientific ZDHHC18 Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:500–1:1,000 |
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host/Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human ZDHHC18. Recombinant protein control fragment (Product #RP-91203) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.3 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2649855 |
Product Specific Information
- Immunogen sequence: NPYSHKSIIT NCCAVLCGPL PPSLIDRRGF VQSDTVLPSP IRSDEPACRA KPDASMVG
- Highest antigen sequence identity: Mouse – 95%, Rat – 98%
Target Information
Zinc-finger proteins contain DNA-binding domains and have diverse functions, including transcriptional activation or repression.
ZDHHC1 (zinc finger, DHHC-type containing 1), also known as ZNF377 or C16orf1, is a 485 amino acid multi-pass membrane protein with one DHHC-type zinc finger. It is expressed in fetal heart, lung, and kidney, and in adult lung and pancreas.
ZDHHC1 functions as a palmitoyltransferase that catalyzes the conversion of palmitoyl-CoA and protein-cysteine to S-palmitoyl protein and CoA.
Like ZDHHC1, ZDHHC5, ZDHHC6, ZDHHC7, and ZDHHC18 each contain one DHHC-type zinc finger and exhibit palmitoyltransferase activity against substrates such as H-Ras, SNAP25, and GABAA R proteins.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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