ELK Biotechnology Calpain 2 rabbit pAb
Calpain 2 rabbit pAb는 인간 Calpain 2 단백질을 인식하는 고품질 다클론 항체로, IHC, IF, ELISA에 적합합니다. 세포질 및 세포막에서 발현되며 Ca2+ 결합 시 막으로 이동합니다. 인간, 생쥐, 랫트 시료에 반응합니다.
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Calpain 2 rabbit pAb
공급업체: ELK Biotechnology
제품 정보
| 항목 | 내용 |
|---|---|
| Product name | Calpain 2 rabbit pAb |
| Alternative Names | CAPN2; CANPL2; Calpain-2 catalytic subunit; Calcium-activated neutral proteinase 2; CANP 2; Calpain M-type; Calpain large polypeptide L2; Calpain-2 large subunit; Millimolar-calpain; M-calpain |
| Applications | IHC; IF; ELISA |
| Recommended Dilutions | Immunohistochemistry: 1/100 - 1/300 ELISA: 1/40000 Not yet tested in other applications |
| Immunogen | The antiserum was produced against synthesized peptide derived from human Calpain 2. AA range: 305-354 |
| Species | Rabbit |
| Storage | -20°C / 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| GeneID (Human) | 824 |
| Human Swiss-Prot No | P17655 |
| Cellular localization | Cytoplasm; Cell membrane; Translocates to the plasma membrane upon Ca(2+) binding |
| Species Reactivity | Human; Mouse; Rat |
Background
The calpains, calcium-activated neutral proteases, are nonlysosomal, intracellular cysteine proteases. The mammalian calpains include ubiquitous, stomach-specific, and muscle-specific proteins. The ubiquitous enzymes consist of heterodimers with distinct large, catalytic subunits associated with a common small, regulatory subunit. This gene encodes the large subunit of the ubiquitous enzyme, calpain 2. Multiple heterogeneous transcriptional start sites in the 5′ UTR have been reported. Two transcript variants encoding different isoforms have been found for this gene.
[provided by RefSeq, Mar 2009]
관련 연구
Experimental Cell Research (2020-01-01)
Inhibition of the ERK1/2-ubiquitous calpains pathway attenuates experimental pulmonary fibrosis in vivo and in vitro
Impact Factor (IF): 3.238
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