ELK Biotechnology CA I rabbit pAb
CA I rabbit pAb는 인간, 랫, 마우스에 반응하는 폴리클로날 항체로 WB, IHC, IF, ELISA 등에 사용 가능. 인간 CA1 유래 합성 펩타이드로 면역화되어 생성되었으며, 29kD 밴드 검출. -20°C에서 1년 보관 가능.
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CA I rabbit pAb
기본 정보
| 항목 | 내용 |
|---|---|
| Alternative Names | CA1; Carbonic anhydrase 1; Carbonate dehydratase I; Carbonic anhydrase B; CAB; Carbonic anhydrase I; CA-I |
| Applications | WB; IHC; IF; ELISA |
| Recommended Dilutions | Western Blot: 1/500 - 1/2000 Immunohistochemistry: 1/100 - 1/300 ELISA: 1/40000 Not yet tested in other applications |
| Immunogen | The antiserum was produced against synthesized peptide derived from human CA1. AA range: 41–90 |
| Host | Rabbit |
| Storage | -20°C / 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 29 kD |
| GeneID (Human) | 759 |
| Human Swiss-Prot No | P00915 |
| Cellular Localization | Cytoplasm |
| Species Reactivity | Human; Rat; Mouse |
Background
Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in various biological processes including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid.
They show extensive diversity in tissue distribution and in their subcellular localization. The CA1 gene is closely linked to the CA2 and CA3 genes on chromosome 8. It encodes a cytosolic protein found at the highest level in erythrocytes. Allelic variants of this gene have been described in some populations. Alternative splicing results in multiple transcript variants.
[provided by RefSeq, May 2014]
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