ELK Biotechnology 14-3-3 γ rabbit pAb
14-3-3 γ 단백질을 인식하는 토끼 폴리클로날 항체로 WB, IHC, IF, ELISA에 사용 가능. 인산화 단백질 신호전달 연구에 적합하며, 사람, 생쥐, 랫트 반응성. 고순도 IgG 형태로 -20°C에서 1년 보관 가능.
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ELK Biotechnology 14-3-3 γ rabbit pAb
제품 정보
| 항목 | 내용 |
|---|---|
| Product name | 14-3-3 γ rabbit pAb |
| Alternative Names | YWHAG; 14-3-3 protein gamma; Protein kinase C inhibitor protein 1; KCIP-1 |
| Applications | WB; IHC; IF; ELISA |
| Recommended Dilutions | Western Blot: 1/500 - 1/2000 Immunohistochemistry: 1/100 - 1/300 Immunofluorescence: 1/200 - 1/1000 ELISA: 1/10000 Not yet tested in other applications |
| Immunogen | The antiserum was produced against synthesized peptide derived from human 14-3-3 gamma (AA range: 51-100) |
| Host | Rabbit |
| Storage | -20°C / 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 28 kD |
| Gene ID (Human) | 7532 |
| Human Swiss-Prot No. | P61981 |
| Cellular Localization | Cytoplasm |
| Species Reactivity | Human; Mouse; Rat |
Background
This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 100% identical to the rat ortholog. It is induced by growth factors in human vascular smooth muscle cells, and is also highly expressed in skeletal and heart muscles, suggesting an important role for this protein in muscle tissue. It has been shown to interact with RAF1 and protein kinase C, proteins involved in various signal transduction pathways. [provided by RefSeq, Jul 2008]
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