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ELK Biotechnology Krs-1/2 (phospho Thr183) rabbit pAb
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인산화 Thr183 부위에 특이적인 Krs-1/2 rabbit polyclonal antibody. WB, IHC, IF, ELISA에 사용 가능하며, 인간 및 마우스 시료에 반응. 세포질 및 핵에서 발현되는 MST1/2 단백질 검출에 적합. -20°C에서 1년 보관.
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- pk
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ELK Biotechnology ES7306-100UL Krs-1/2 (phospho Thr183) rabbit pAb, 100UL pk판매 단위 pk ·
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402,000원VAT 포함 442,200원
ELK Biotechnology ES7306-50UL Krs-1/2 (phospho Thr183) rabbit pAb, 50UL pk판매 단위 pk ·
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301,000원VAT 포함 331,100원
ELK Biotechnology · ELK Biotechnology Krs-1/2 (phospho Thr183) rabbit pAb
제품명
Krs-1/2 (phospho Thr183) rabbit pAb
제품 정보
| 항목 | 내용 |
|---|---|
| Alternative Names | STK3; KRS1; MST2; Serine/threonine-protein kinase 3; Mammalian STE20-like protein kinase 2; MST-2; STE20-like kinase MST2; Serine/threonine-protein kinase Krs-1; STK4; KRS2; MST1; Serine/threonine-protein kinase 4; Mammalian STE20-like protein kinase |
| Applications | WB; IHC; IF; ELISA |
| Recommended Dilutions | Western Blot: 1/500 - 1/2000 Immunohistochemistry: 1/100 - 1/300 ELISA: 1/40000 Not yet tested in other applications |
| Immunogen | The antiserum was produced against synthesized peptide derived from human Mst1/2 around the phosphorylation site of Thr183 (AA range: 149–198) |
| Host | Rabbit |
| Storage | -20°C / 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 60 kD |
| Gene ID (Human) | 6789 |
| Human Swiss-Prot No. | Q13188 / Q13043 |
| Cellular Localization | Cytoplasm, Nucleus. The caspase-cleaved form cycles between nucleus and cytoplasm (PubMed:19525978, PubMed:11278283). Phosphorylation at Thr-117 leads to inhibition of nuclear translocation (PubMed:19525978). |
| Species Reactivity | Human, Mouse |
Background
Serine/threonine kinase 3 (STK3) Homo sapiens.
This gene encodes a serine/threonine protein kinase activated by proapoptotic molecules, indicating its role as a growth suppressor. Cleavage by caspase removes the inhibitory C-terminal portion, and the N-terminal portion translocates to the nucleus, forming an active kinase that promotes chromatin condensation during apoptosis. Multiple transcript variants encoding different isoforms have been identified (RefSeq, Jan 2012).
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