
Thermo Fisher Scientific TRPM8 Polyclonal Antibody
TRPM8 단백질을 인식하는 Thermo Fisher Scientific의 폴리클로날 항체로, Western blot 및 IHC에 적합합니다. 냉각 감지 관련 TRPM8 채널 연구용으로 사용되며, Reptile 반응성 및 Rabbit 유래 항체입니다. 장기 보관 시 -20°C에서 안정적으로 유지됩니다.
- 카탈로그번호
- OST00163W-100UL
- 판매단위
- pk
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Applications
Western Blot (WB)
- Tested Dilution: 1:300–1:2,000
Immunohistochemistry (IHC)
- Tested Dilution: 1:300–1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Reptile |
| Host / Isotype | Rabbit / Ig |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide from crocodile TRPM8 (Transient receptor potential cation channel 8) conjugated to an immunogenic carrier protein |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | Not determined |
| Storage Buffer | Whole serum |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for added stability. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Reconstitute in 100 µL of sterile water.
- Centrifuge to remove any insoluble material.
- Specificity: TRPM8.
Target Information
TRPM8 is a receptor-activated non-selective cation channel involved in detection of sensations such as coolness, activated by cold temperature below 25 °C. It responds to icilin, eucalyptol, menthol, cold, and intracellular pH modulation, and is permeable to Na⁺, K⁺, Cs⁺, and Ca²⁺.
TRPM8 expression is mainly restricted to prostate epithelial cells, moderately expressed in normal prostate tissue, and elevated in prostate cancer. TRPM8 mRNA is also found in certain nonprostatic tumors (breast, colon, lung, skin), but rarely detected in corresponding normal tissues.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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