Thermo Fisher Scientific UCP4 Polyclonal Antibody
UCP4 단백질을 인식하는 토끼 다클론 항체로, Western blot에 최적화되어 있습니다. 마우스 반응성이 있으며, 고순도 친화 크로마토그래피 정제 제품입니다. 미토콘드리아 탈결합 단백질 연구용으로 적합합니다. 연구용으로만 사용 가능합니다.
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Applications
- Western Blot (WB): 1.0 µg/mL
- View 2 publications
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Mouse |
| Published Species | Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to a region of mouse UCP4 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 2% sucrose |
| Contains | 0.09% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2691117 |
Product Specific Information
This target displays homology in the following species:
Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Sheep: 100%; Zebrafish: 85%.
Target Information
UCP4 is a 323 amino acid mitochondrial uncoupling protein belonging to the large mitochondrial substrate carrier family with three Solcar repeats. UCP4 acts as a mitochondrial transport carrier that facilitates the transfer of anions from the inner to the outer mitochondrial membrane and the return transfer of protons in the opposite direction. It reduces the mitochondrial membrane potential and is involved in thermoregulatory heat production. By creating proton leaks across the inner mitochondrial membrane, UCP4 uncouples oxidative phosphorylation from ATP synthesis, dissipating energy as heat. UCP4 is primarily expressed in adult and fetal brain, with lower expression in spinal cord, corpus callosum, and substantia nigra.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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