Thermo Fisher Scientific Phospho-DNM1L (Ser616) Polyclonal Antibody
Phospho-DNM1L (Ser616)에 특이적인 Rabbit Polyclonal Antibody로, 인산화된 DRP1 단백질 검출에 적합. Western blot에 최적화되어 있으며, Human 및 Mouse 시료에 반응. PBS/glycerol buffer에 보관하며 연구용으로 사용.
- 카탈로그번호
- PA5101030
- 판매단위
- pk
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Applications
Western Blot (WB)
- Tested Dilution: 1:1,000–1:3,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human DNM1L (Accession O00429), corresponding to amino acid residues around phosphorylated Ser616 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Sequential chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2815859 |
Product Specific Information
This antibody detects endogenous levels of DRP1 only when phosphorylated at Ser616.
Target Information
DRP1 (Dynamin-related protein 1) is a human mitochondrial GTPase involved in mitochondrial division. It plays a critical role in mitochondrial fission during steady state and apoptosis. Proper DRP1 function ensures correct mitochondrial distribution; in mutant neurons, mitochondria are largely absent from synapses, providing a tool to study mitochondrial roles in neuronal function.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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