Thermo Fisher Scientific MVP Polyclonal Antibody
Thermo Fisher Scientific의 MVP Polyclonal Antibody는 인간 MVP 단백질을 인식하는 토끼 유래 IgG 항체입니다. Western blot 및 IHC(P) 분석에 최적화되어 있으며, 높은 특이성과 재현성을 제공합니다. 연구용으로만 사용되며 장기 보관 시 -20°C에서 안정적으로 유지됩니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:1,000–1:2,500 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human MVP. Recombinant protein control fragment (Product #RP-105340). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.2 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2791818 |
Product Specific Information
Immunogen sequence:
KVSHQAGDHW LIRGPLEYVP SAKVEVVEER QAIPLDENEG IYVQDVKTGK VRAVIGSTYM LTQDEVLWEK ELPPGVEELL NKGQDPLAD
Target Information
This gene encodes the major vault protein (MVP), a lung resistance-related protein. Vaults are multi-subunit structures that may be involved in nucleo-cytoplasmic transport. MVP mediates drug resistance, possibly via a transport process. It is widely distributed in normal tissues and overexpressed in multidrug-resistant cancer cells. Overexpression serves as a potential marker of clinical drug resistance. This gene produces two transcripts using alternative exon 2 sequences, but both share the same open reading frame.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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