
Thermo Fisher Scientific GGA1 Polyclonal Antibody
Thermo Fisher Scientific의 GGA1 폴리클로날 항체는 Human GGA1 단백질을 타깃으로 제작된 Rabbit IgG 항체입니다. Western blot과 IHC(P)에서 검증되었으며, 항원 친화 크로마토그래피로 정제되었습니다. 다양한 종에서 예측 반응성을 보여 연구용으로 적합합니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:3,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:1,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fragment corresponding to a region within amino acids 46–307 of Human GGA1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7, with 1% BSA, 20% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2547410 |
Product Specific Information
- Recommended positive controls: NT2D1, PC-3, U87-MG, SK-N-SH
- Predicted reactivity: Mouse (95%), Rat (96%), Xenopus laevis (81%), Bovine (96%)
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
This gene encodes an apoptosis inhibitory protein whose expression prevents apoptosis after growth factor deprivation.
It suppresses the transcription factor E2F1-induced apoptosis and interacts with, and negatively regulates, Acinus—a nuclear factor involved in apoptotic DNA fragmentation.
Depletion of this protein enhances the cytotoxic action of chemotherapeutic drugs.
Multiple alternatively spliced transcript variants encoding different isoforms have been identified.
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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