Thermo Fisher Scientific TMEM66 Polyclonal Antibody
TMEM66 단백질을 표적으로 하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot에 적합하며, SOCE 관련 단백질 연구에 활용 가능. 동결건조 형태로 제공되며 -20°C에서 보관. 연구용으로만 사용 가능.
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Applications
- Western Blot (WB): Tested dilution 1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Peptide (C)ELGLSKLKESGKHQS, corresponding to amino acid residues 141–155 of rat SOCE-associated regulatory factor |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 0.85 mg/mL |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2736711 |
Product Specific Information
Product is shipped at room temperature as a lyophilized powder and should be stored at -20°C upon receipt.
Reconstitution: add 50 µL of deionized water.
Target Information
Saraf encodes a protein that is a negative regulator of store-operated Ca(2+) entry (SOCE), involved in protecting cells from Ca(2+) overfilling.
In response to cytosolic Ca(2+) elevation after endoplasmic reticulum Ca(2+) refilling, it promotes a slow inactivation of STIM (STIM1 or STIM2)-dependent SOCE activity.
It possibly acts by facilitating the de-oligomerization of STIM to efficiently turn off ORAI when the endoplasmic reticulum lumen is filled with appropriate Ca(2+) levels, preventing cellular Ca(2+) overload.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(PA5-77334_TMEM66_Q6AYN2-1_Rabbit.svg / PA5-77334_TMEM66_Q6AYN2-1_Rabbit_PDP.jpeg)
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