Thermo Fisher Scientific MEIOB Polyclonal Antibody
인간 MEIOB 단백질을 인식하는 Rabbit Polyclonal Antibody로, IHC(P)에서 1:25~1:100 희석으로 검증됨. 액상 형태이며 PBS/glycerol buffer에 보관. DNA 복제 및 재조합 연구용으로 적합. 연구용 전용 제품.
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:25–1:100
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host/Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic protein corresponding to residues near the C-terminal of human MEIOB |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.7 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.4, with 40% glycerol |
| Contains | 0.05% sodium azide |
| Storage conditions | -20°C |
| Shipping conditions | Wet ice |
| RRID | AB_2688502 |
Target Information
Single-stranded DNA-binding protein required for homologous recombination in meiosis I.
Required for double strand breaks (DSBs) repair, crossover formation, and promotion of faithful and complete synapsis.
Not required for the initial loading of recombinases but necessary to maintain proper RAD51 and DMC1 foci after the zygotene stage.
May act by stabilizing recombinases, essential for successful homology search and meiotic recombination.
Displays single-stranded DNA 3′–5′ exonuclease activity in vitro.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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