Thermo Fisher Scientific CD119 (IFN gamma Receptor 1) Monoclonal Antibody (2E2), PE, eBioscience

Thermo Fisher Scientific CD119 (IFN gamma Receptor 1) Monoclonal Antibody (2E2), PE, eBioscience™

Applications

• Flow Cytometry (Flow)

Tested Dilution: 1 µg/test
Publications: View 13 publications

Product Specifications

Additional Formats:

• Biotin
• Request custom conjugation

Product Specific Information

The monoclonal antibody 2E2 recognizes mouse CD119, also known as IFN gamma receptor 1. CD119 heterodimerizes with IFN gamma receptor 2 (AF-1), forming the Class II cytokine receptor.
IFN gamma binds to the IFN gamma receptor 1 subunit, while signal transduction occurs via receptor 2.
The receptor is involved in host defense and is broadly expressed in B cells, NK cells, macrophages, dendritic cells, and various non-hematopoietic cells.

Applications Reported: Flow cytometric analysis.
Applications Tested: Tested on mouse splenocytes at ≤1 µg/test (100 µL final volume).
Cell number should be empirically determined (10⁵–10⁸ cells/test).
Recommended incubation: 60 minutes at 2–8°C for optimal staining.

Excitation: 488–561 nm
Emission: 578 nm
Laser Compatibility: Blue, Green, Yellow-Green lasers
Filtration: 0.2 µm post-manufacturing filtered

Target Information

The IFNGR1 gene encodes the ligand-binding chain (alpha) of the gamma interferon receptor.
Human interferon-gamma receptor is a heterodimer of IFNGR1 and IFNGR2.
Genetic variations in IFNGR1 are associated with susceptibility to Helicobacter pylori infection.
Defects in IFNGR1 can cause mendelian susceptibility to mycobacterial disease (familial disseminated atypical mycobacterial infection).

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

제품 이미지