Thermo Fisher Scientific CD119 (IFN gamma Receptor 1) Monoclonal Antibody (2E2), PE, eBioscience
Mouse CD119 (IFNγ Receptor 1) 인식하는 단클론 항체로, PE 형광표지되어 Flow Cytometry에 최적화됨. 2E2 클론, Armenian hamster IgG, 0.2 mg/mL 농도. 488–561 nm 여기, 578 nm 방출. 4°C 암조건 보관, 동결 금지.
- 카탈로그번호
- 12-1191-8x (2개 옵션)
- 판매단위
- pk
카탈로그
2개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific CD119 (IFN gamma Receptor 1) Monoclonal Antibody (2E2), PE, eBioscience
Thermo Fisher Scientific CD119 (IFN gamma Receptor 1) Monoclonal Antibody (2E2), PE, eBioscience™
Applications
- Flow Cytometry (Flow)
Tested Dilution: 1 µg/test
Publications: View 13 publications
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Mouse |
| Published Species | Mouse |
| Host / Isotype | Armenian hamster / IgG |
| Recommended Isotype Control | Armenian Hamster IgG Isotype Control (eBio299Arm), PE, eBioscience™ |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 2E2 |
| Conjugate | PE |
| Excitation / Emission Max | 565 / 576 nm |
| Form | Liquid |
| Concentration | 0.2 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.2 |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C, store in dark, DO NOT FREEZE |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_1210731 |
Additional Formats:
Product Specific Information
The monoclonal antibody 2E2 recognizes mouse CD119, also known as IFN gamma receptor 1. CD119 heterodimerizes with IFN gamma receptor 2 (AF-1), forming the Class II cytokine receptor.
IFN gamma binds to the IFN gamma receptor 1 subunit, while signal transduction occurs via receptor 2.
The receptor is involved in host defense and is broadly expressed in B cells, NK cells, macrophages, dendritic cells, and various non-hematopoietic cells.
Applications Reported: Flow cytometric analysis.
Applications Tested: Tested on mouse splenocytes at ≤1 µg/test (100 µL final volume).
Cell number should be empirically determined (10⁵–10⁸ cells/test).
Recommended incubation: 60 minutes at 2–8°C for optimal staining.
Excitation: 488–561 nm
Emission: 578 nm
Laser Compatibility: Blue, Green, Yellow-Green lasers
Filtration: 0.2 µm post-manufacturing filtered
Target Information
The IFNGR1 gene encodes the ligand-binding chain (alpha) of the gamma interferon receptor.
Human interferon-gamma receptor is a heterodimer of IFNGR1 and IFNGR2.
Genetic variations in IFNGR1 are associated with susceptibility to Helicobacter pylori infection.
Defects in IFNGR1 can cause mendelian susceptibility to mycobacterial disease (familial disseminated atypical mycobacterial infection).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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