Thermo Fisher Scientific COL17A1 Polyclonal Antibody
Human COL17A1 단백질을 인식하는 Rabbit Polyclonal Antibody로 Western Blot 및 Flow Cytometry에 적합. KLH 결합 합성 펩타이드(aa 475-504)를 면역원으로 사용. Protein A 및 항원 친화 크로마토그래피로 정제. PBS 완충액에 0.09% sodium azide 포함, 장기 보관은 -20°C 권장.
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Applications
Western Blot (WB)
- Tested Dilution: 1:2,000
Flow Cytometry (Flow)
- Tested Dilution: 1:25
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic peptide between 475–504 amino acids from the central region of human COL17A1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.45 mg/mL |
| Purification | Protein A, Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | 0.09% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2543608 |
Target Information
COL17A1 is the alpha chain of type XVII collagen. Unlike most collagens, collagen XVII is a transmembrane protein and a structural component of hemidesmosomes, multiprotein complexes at the dermal-epidermal basement membrane zone that mediate adhesion of keratinocytes to the underlying membrane.
COL17A1 belongs to the FACIT collagen family (fibril-associated collagens with interrupted helices) and is localized to tissues containing type I collagen, potentially contributing to extracellular matrix integrity.
Diseases associated with COL17A1 dysfunction include epithelial recurrent erosion dystrophy and epidermolysis bullosa.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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