Thermo Fisher Scientific RyR3 Polyclonal Antibody
Human RyR3 단백질을 인식하는 Rabbit Polyclonal Antibody로, IHC, ICC/IF, ELISA, Dot blot 등에 사용 가능. 고순도 Affinity Chromatography 정제, 1 mg/mL 농도. 세포 내 칼슘 방출 관련 연구용에 적합.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:100 |
| ELISA | 1:5,000–1:10,000 |
| Dot blot (DB) | 1:2,000–1:20,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein within Human RYR3 (aa 1–140) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol, 0.2% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | −20°C, avoid freeze/thaw cycles, store in dark |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2854732 |
Product Specific Information
Positive Control: Lovo, rat brain tissue, human kidney tissue, human placenta tissue, mouse brain tissue.
Target Information
RYR3 is a ryanodine receptor that releases calcium from intracellular stores for use in various cellular processes. It is involved in skeletal muscle contraction by releasing calcium from the sarcoplasmic reticulum following T-tubule depolarization. Two transcript variants encoding different isoforms of RYR3 have been identified. RYR3 mediates Ca²⁺ release from the sarcoplasmic reticulum into the cytoplasm and contributes to calcium ion homeostasis and signaling. Diseases associated with RYR3 include Central Core Disease and Arrhythmogenic Right Ventricular Dysplasia 2.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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