Thermo Fisher Scientific DDX56 Monoclonal Antibody (OTI6E8), TrueMAB
인간 DDX56 단백질을 인식하는 마우스 단클론 항체로, Western blot 및 IHC(P)에서 검증됨. 동결건조 형태로 제공되며, 재구성 후 약 1 mg/mL 농도로 사용 가능. RNA 헬리케이스 연구 및 리보솜 합성 관련 연구에 적합.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:150 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI6E8 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 323–547 of human DDX56 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL of distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, it is recommended to perform an additional desalting step (e.g., Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
The DDX56 gene encodes a member of the DEAD box protein family, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD). These proteins function as putative RNA helicases and are involved in various cellular processes such as translation initiation, RNA splicing, and ribosome assembly.
DDX56 exhibits ATPase activity in the presence of polynucleotides and associates with nucleoplasmic 65S preribosomal particles, suggesting a role in ribosome synthesis, particularly in the assembly of the large 60S ribosomal subunit.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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