Thermo Fisher Scientific ASH2L Polyclonal Antibody
Thermo Fisher Scientific의 ASH2L Polyclonal Antibody는 인간 ASH2L 단백질을 인식하는 토끼 다클론 항체로, WB 및 ELISA에 최적화되었습니다. 핵 내 단백질 검출에 적합하며, 고순도 친화 크로마토그래피 정제 및 안정한 PBS/glycerol buffer로 제공됩니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| ELISA | 1 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 81–280 of human ASH2L (NP_001098684.1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.02 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | −20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2805828 |
Product Specific Information
Immunogen sequence:
NLTWQSRTQD EHPKTMFSKD KDIIPFIDKY WECMTTRQRP GKMTWPNNIV KTMSKERDVF LVKEHPDPGS KDPEEDYPKF GLLDQDLSNI GPAYDNQKQS SAVSTSGNLN GGIAAGSSGK GRGAKRKQQD GGTTGTTKKA RSDPLFSAQR LPPHGYPLEH PFNKDGYRYI LAEPDPHAPD PEKLELDCWA GKPIPGDLYR
Positive Samples: K-562, HepG2
Cellular Location: Nucleus
Target Information
The human ASH2L gene encodes a 628 amino acid protein (ASH2L1, isoform 1) containing a nuclear localization signal and a PHD finger motif, suggesting a role as a transcription regulator.
- Predicted molecular weight: 68.7 kDa
- Alternative splicing may produce isoforms of 60 kDa and 56.5 kDa
- 60% homologous to Drosophila ash2 and 90% to mouse ASH2L
- Expressed predominantly in adult heart and testis, and fetal lung and liver
- Low expression in adult lung, liver, kidney, prostate, and peripheral leukocytes
- Involved in hematopoiesis and certain leukemia types
- Suggested to interact with β-tubulin and β-catenin
Safety Information
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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