Thermo Fisher Scientific PAOX Polyclonal Antibody
PAOX 단백질을 표적으로 하는 Rabbit Polyclonal Antibody로, Western Blot 및 IHC(Paraffin) 실험에 적합. Human 반응성, Unconjugated 형태, 고순도 affinity chromatography 정제. 연구용으로만 사용 가능.
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Applications
Western Blot (WB)
- Tested Dilution: 1:1,000–1:3,000
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:100
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthesized peptide derived from human PAOX (UniProt ID: Q6QHF9-2, Range: 299–321, Length: 511) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2691590 |
Target Information
Flavoenzyme which catalyzes the oxidation of N(1)-acetylspermine to spermidine and is thus involved in the polyamine back-conversion (PubMed:12477380). Can also oxidize N(1)-acetylspermidine to putrescine.
Substrate specificity: N(1)-acetylspermine = N(1)-acetylspermidine > N(1),N(12)-diacylspermine >> spermine.
Does not oxidize spermidine. Plays an important role in the regulation of polyamine intracellular concentration and may determine cellular sensitivity to antitumor polyamine analogs (PubMed:12477380). [UniProt]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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