Thermo Fisher Scientific Felvizumab Chimeric Recombinant Rabbit Monoclonal Antibody (RSHZ19 (Felvizumab))
RSV F 단백질 특이적 키메라 재조합 토끼 단클론 항체. ELISA 및 기능적 분석에 적합. HEK293 세포에서 발현된 비결합형 항체로, 1 mg/mL 농도. 단백질 A로 정제되어 높은 순도 유지. 단기 4°C, 장기 -20°C 보관 권장.
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Applications
ELISA (ELISA)
- Tested Dilution: Assay-dependent
Functional Assay (Functional)
- Tested Dilution: Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Virus |
| Host / Isotype | Rabbit / IgG, kappa |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | RSHZ19 (Felvizumab) |
| Immunogen | This antibody was prepared by the humanization of an F protein-specific murine MAb, RSV19. Molecular techniques were used to insert the complementarity determining regions from murine RSV19 into a human IgG1 heavy and k light chain-variable domain framework. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_3074497 |
Product Specific Information
Specificity:
This antibody is specific for an epitope located between amino acids 417–432 of the conserved fusion (F) protein of RSV.
Target Information
Felvizumab is a biosimilar that targets RSV.
Human respiratory syncytial virus (RSV) is a member of the Paramyxoviridae family, subfamily Pneumovirinae, that causes common respiratory tract infections such as measles and mumps.
Its genome consists of single-stranded, negative-sense RNA that encodes three envelope glycoproteins: a small hydrophobic (SH) protein of unknown function, a major glycoprotein (G) known as the attachment protein, and a fusion (F) protein.
The F proteins on the virus surface cause membranes of nearby cells to merge, forming syncytia.
While RSV typically produces mild symptoms in adults, it is a leading cause of lower respiratory tract infections and hospital visits during infancy and childhood.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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