Thermo Fisher Scientific PZP Polyclonal Antibody

Applications

Western Blot (WB)

• Tested Dilution: 1:500–1:2,000
• View 1 publication

ELISA

• Tested Dilution: 1 µg/mL
• View reference

Product Specifications

Product Specific Information

Immunogen sequence:
VKDLTNFPDN VDQQEEEQGH CPRPFFIHNG AIYVPLSSNE ADIYSFLKGM GLKVFTNSKI RKPKSCSVIP SVSAGAVGQG YYGAGLGVVE RPYVPQLGTY NVIPLNNEQS SGPVPETVRS Y

Target Information

The protein encoded by this gene is highly expressed in late-pregnancy serum and is similar in structure to alpha-2-macroglobulin. The encoded protein, which acts as a homotetramer, inhibits the activity of all four classes of proteinases. This protein contains cleavage sites for several proteinases. Upon binding of a proteinase, the conformation of this protein changes to trap the proteinase, limiting its activity. This protein appears to be elevated in the sera of presymptomatic Alzheimer’s disease patients.

⚠ WARNING:
This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.

For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.