Thermo Fisher Scientific Det1 Polyclonal Antibody

Applications

Tested Dilution

Publications

Immunohistochemistry (Paraffin) (IHC (P))

1:500-1:1,000

-

Immunocytochemistry (ICC/IF)

0.25-2 µg/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human Det1. Recombinant protein control fragment (Product #RP-98102). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:DET1,uniProtId:Q7L5Y6-1,ncbiNodeId:9606,antigenRange:34-145,antigenLength:550,antigenImageFileName:PA5-61826_DET1_Q7L5Y6-1_Rabbit.svg,antigenImageFileNamePDP:PA5-61826_DET1_Q7L5Y6-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.2 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2640539

Product Specific Information

Immunogen sequence: THWHQVRVFH QNVFPNFTVV NVEKPPCFLR KFSPDGRYFI AFSSDQTSLE IYEYQGCQAA EDLLQGYEGE ILSNGNDQRS VNIRGRLFER FFVLLHITNV AANGEHLNRE CS

Highest antigen sequence identity to the following orthologs: Mouse - 99%, Rat - 99%.

Target Information

DET1 is a component of the E3 ubiquitin ligase DCX DET1-COP1 complex, which is required for ubiquitination and subsequent degradation of target proteins. The complex is involved in JUN ubiquitination and degradation.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.