Thermo Fisher Scientific ITGB1 Monoclonal Antibody (4B7R), FITC
인간 CD29(Integrin β1)을 인식하는 FITC 결합 단일클론 항체로, 유세포 분석(FACS), 면역세포화학, 면역조직화학 등에 적합합니다. 단백질 A로 정제되었으며, PBS/BSA 완충액에 보관됩니다. 4°C 단기, -20°C 장기 보관 권장.
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Thermo Fisher Scientific ITGB1 Monoclonal Antibody (4B7R), FITC
Applications and Tested Dilutions
| Application | Tested Dilution | Publications |
|---|---|---|
| Immunohistochemistry (IHC) | - | View 3 publications |
| Immunocytochemistry (ICC/IF) | - | View 2 publications |
| Flow Cytometry (Flow) | Neat | View 2 publications |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Published Species | Human, Mouse |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 4B7R |
| Immunogen | Ocular melanoma cell line V+B2 |
| Conjugate | FITC |
| Excitation / Emission Max | 498 / 517 nm |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS, pH 7.4, with 1% BSA |
| Contains | 0.09% sodium azide |
| Storage Conditions | Store at 4°C short term; for long term, store at -20°C. Avoid freeze/thaw cycles. Store in the dark. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_928062 |
Additional Formats
Product Specific Information
For FACS analysis, use 10 µL of the suggested working dilution to label 1×10^6 cells in 100 µL.
Mouse anti-Human CD29 monoclonal antibody, clone 4B7R, recognizes the human integrin beta 1 subunit (CD29), a ~130 kDa (red) / 115 kDa (non-red) single-pass type I transmembrane glycoprotein expressed by most leukocytes and mesenchymal stem cells.
Target Information
ITGB1 (Integrin Subunit Beta 1, CD29) is a 110 kDa cell surface glycoprotein widely expressed by various cell types, including all leukocytes. It forms non-covalent heterodimers with multiple alpha chains (α1–α6), defining the binding properties of β1 (VLA) integrins.
ITGB1 functions as a cell adhesion molecule and is involved in immune cell trafficking, tissue damage regulation, and inflammatory responses. Decreased ITGB1 expression is associated with multidrug resistance in tumor cells.
Two major isoforms, β1A and β1D, differ by 13 amino acids and exhibit tissue-specific distribution: β1A in most tissues, β1D in cardiac and skeletal muscle.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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