Thermo Fisher Scientific GRTP1 Polyclonal Antibody

Applications

Tested Dilution

Publications

Immunohistochemistry (Paraffin) (IHC (P))

1:20-1:50

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human GRTP1. Recombinant protein control fragment (Product #RP-97976). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:GRTP1,uniProtId:Q5TC63-1,ncbiNodeId:9606,antigenRange:265-329,antigenLength:336,antigenImageFileName:PA5-61182_GRTP1_Q5TC63-1_Rabbit.svg,antigenImageFileNamePDP:PA5-61182_GRTP1_Q5TC63-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.05 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2642228

Product Specific Information

Immunogen sequence: VALTLIKQHQ ELILEATSVP DICDKFKQIT KGSFVMECHT FMQKIFSEPG SLSMATVAKL RESCR

Highest antigen sequence identity to the following orthologs: Mouse - 83%, Rat - 89%.

Target Information

GRTP1, also known as germ cell-specific gene 1-related protein, is a protein that is expressed in the testis and is involved in the regulation of spermatogenesis, the process of sperm cell development. It is a member of the GRP family of proteins, which are characterized by a conserved motif called the GRP domain. GRTP1 is thought to play a role in the differentiation of spermatogonia into spermatocytes and in the regulation of meiosis, the process of cell division that produces haploid cells. Mutations in the GRTP1 gene have been associated with male infertility. GRTP1 was identified as an HIV dependency factor (HDF), suggesting that GRTP1 may be an important drug target in HIV treatment.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.