Thermo Fisher Scientific TMEM27 Polyclonal Antibody
Rabbit polyclonal antibody targeting TMEM27, reactive with mouse and rat. Suitable for WB and ELISA. Affinity purified, liquid form, stored at -20°C. Useful for detecting TMEM27 in kidney and pancreas tissues.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| ELISA | 1 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 1–222 of human TMEM27 (NP_065716.1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.51 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2805089 |
Product Specific Information
Immunogen sequence:
MLWLLFFLVT AIHAELCQPG AENAFKVRLS IRTALGDKAY AWDTNEEYLF KAMVAFSMRK VPNREATEIS HVLLCNVTQR VSFWFVVTDP SKNHTLPAVE VQSAIRMNKN RINNAFFLND QTLEFLKIPS TLAPPMDPSV PIWIIIFGVI FCIIIVAIAL LILSGIWQRR RKNKEPSEVD DAEDKCENMI TIENGIPSDP LDMKGGHIND AFMTEDERLT PL
Positive Samples: Mouse Kidney, Mouse Pancreas, Rat Kidney
Cellular Location: Membrane, Single-pass type I membrane protein
Target Information
TMEM27 (Transmembrane protein 27), also known as collectrin, belongs to the TMEM27 family. It stimulates beta cell replication and is a membrane protein cleaved and shed by pancreatic beta cells, proposed as a beta cell mass biomarker. Western blot analysis of mouse collecting duct cell lines detected Tmem27 at an apparent molecular mass of 32 kDa. TMEM27 is an N-glycosylated protein forming dimers with a molecular weight of 64–75 kDa.
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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