Thermo Fisher Scientific MDC1 Polyclonal Antibody
MDC1 단백질을 인식하는 Rabbit Polyclonal 항체로, WB, IHC, ICC/IF, ELISA 등 다양한 응용에 사용 가능. Human 및 Mouse 반응성. Affinity Chromatography로 정제된 액상형 제품으로, -20°C에서 보관. DNA 손상 반응 연구에 적합.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| ELISA | 1 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to amino acids 1–100 of human MDC1 (NP_055456.2) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.54 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.09% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2805088 |
Product Specific Information
- Immunogen sequence: MEDTQAIDWD VEEEEETEQS SESLRCNVEP VGRLHIFSGA HGPEKDFPLH LGKNVVGRMP DCSVALPFPS ISKQHAEIEI LAWDKAPILR DCGSLNGTQI
- Positive Samples: Mouse testis
- Cellular Location: Chromosome, Nucleus
Target Information
MDC1 participates in the early response to DNA damage. It is a member of the BRCT (BRCA1 C-terminus) superfamily of nuclear proteins. MDC1 contains an N-terminal forkhead-associated (FHA) motif, two C-terminal BRCT motifs, and 13 internal repeats of a 41-amino acid sequence.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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