Thermo Fisher Scientific HOXB4 Polyclonal Antibody
HOXB4 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. IHC(P)에서 5 µg/mL로 검증됨. 액상 형태, 0.5 mg/mL 농도. 줄기세포 및 조혈 분화 연구에 적합하며, 연구용으로만 사용.
- 카탈로그번호
- PA523394
- 판매단위
- pk
카탈로그
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Applications
- Immunohistochemistry (Paraffin) (IHC (P)): 5 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide (11 NYVDPKFPPCEEYSQSDYL 29) of HOXB4 protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2540917 |
Target Information
HOX homeobox genes play a role both in the early stem cell function as well as in later stages of hematopoietic differentiation.
HOXB4, specifically, is a homeotic selector gene implicated in self-renewal of definitive HSCs.
Expression of HOXB4 in primitive progenitors combined with culture on hematopoietic stroma induced a switch to the definitive HSC phenotype.
Activation of WNT signaling in HSCs induced increased expression of HOXB4.
Perturbations of HOX gene expression can cause leukemia.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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