Thermo Fisher Scientific Rwdd1 Polyclonal Antibody
Human Rwdd1 단백질에 특이적인 Rabbit Polyclonal Antibody로, IHC(P)에서 1:20~1:50 희석 비율로 검증됨. 항원 친화 크로마토그래피로 정제되었으며 PBS/glycerol buffer에 보존. 연구용으로 세포 형태학 및 단백질 발현 분석에 적합.
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:20–1:50
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human Rwdd1 (Recombinant protein control fragment: Product #RP-94635) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.05 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C (short term). For long-term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2646885 |
Product Specific Information
Immunogen sequence:
ALESIYPDSF TVLSENPPSF TITVTSEAGE NDETVQTTLK FTYSEKYPDE APLYEIFSQE NLEDNDVSD
Highest antigen sequence identity to the following orthologs:
- Mouse: 97%
- Rat: 100%
Target Information
The Formin-like protein 1 (FRL1) gene encodes a formin-related protein implicated in morphogenesis, cytokinesis, and cell polarity. Formins are a conserved class of proteins expressed in all eukaryotes and contain:
- DAD (diaphanous autoregulatory domain)
- FH2 (formin homology 2) domain
- GBD/FH3 (Rho GTPase-binding / formin homology 3) domain
FRL1 is located in the cytoplasm and is highly expressed in spleen, lymph node, and bone marrow cells. It may play a role in cell motility, macrophage survival, and cytoskeletal organization.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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