Thermo Fisher Scientific RGS14 Polyclonal Antibody
RGS14 단백질을 표적으로 하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot 및 Immunoprecipitation에 적합하며, 고순도 액상 형태로 제공. 4°C 보관, 1년 권장 보관 기간. 연구용으로만 사용 가능.
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Applications
Western Blot (WB)
- Tested Dilution: 1:2,000–1:10,000
Immunoprecipitation (IP)
- Tested Dilution: 2–10 µg/mg lysate
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 516 and 566 of Human Regulator of G-Protein Signaling 14 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
The recommended shelf life for this product is 1 year from date of receipt.
Target Information
RGS14 is a member of the regulator of G-protein signaling family, containing one RGS domain, two Raf-like Ras-binding domains (RBDs), and one GoLoco domain.
It attenuates G-protein signaling by binding to activated, GTP-bound G alpha subunits and acts as a GTPase activating protein (GAP), facilitating conversion of GTP to GDP.
RGS14 also modulates microtubule polymerization and spindle organization, plays a role in cell division, and is required for NGF-mediated neurite outgrowth.
Additionally, RGS14 is implicated in stress resistance, visual memory processing, and hippocampal-based learning and memory.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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