Thermo Fisher Scientific FASN Polyclonal Antibody
Human, Mouse, Rat에서 반응하는 FASN 다클론 항체로 Western blot, IHC, ICC에 적합. Protein A로 정제된 액상 항체이며, PBS/glycerol buffer에 보관. 세포질 내 FASN 단백질 검출에 유용하며, 암세포 연구에 활용 가능.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein within human Fatty Acid Synthase (aa 801–1050) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol, 0.2% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2913591 |
Product Specific Information
- Positive Control: A549, MCF-7, HeLa, human prostate tissue, human breast cancer tissue
- Subcellular Location: Cytoplasm, Melanosome
Target Information
Fatty acid synthase (FASN) is a multifunctional enzyme that catalyzes the synthesis of palmitate from acetyl-CoA and malonyl-CoA in the presence of NADPH, leading to the formation of long-chain saturated fatty acids. In some cancer cell lines, FASN has been found to fuse with estrogen receptor-alpha (ER-alpha), where the N-terminus of FAS is fused in-frame with the C-terminus of ER-alpha.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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