Thermo Fisher Scientific TXNL4B Recombinant Rabbit Monoclonal Antibody (002)
인간 TXNL4B 단백질을 인식하는 재조합 토끼 단클론 항체입니다. ELISA에 적합하며 높은 특이성과 일관된 품질을 제공합니다. 보존제가 포함되지 않아 필요 시 아지드 추가를 권장합니다. 단백질 A로 정제되었으며 4°C 또는 -20°C에서 보관 가능합니다.
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Applications and Tested Dilution
- Application: ELISA
- Tested Dilution: 1:5,000–1:10,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 002 |
| Immunogen | Recombinant Human Dim2/TXNL4B protein (Met1–Ile149) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2786643 |
Product Specific Information
This product is preservative-free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%–0.1%).
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. These systems are developed by cloning specific antibody DNA sequences from immunoreactive rabbits. Individual clones are screened to select the best candidates for production.
Advantages of recombinant rabbit monoclonal antibodies:
- Better specificity and sensitivity
- Lot-to-lot consistency
- Animal origin-free formulations
- Broader immunoreactivity due to larger rabbit immune repertoire
This antibody specifically recognizes Human Dim2/TXNL4B.
Target Information
Dim2, also known as TXNL4B (thioredoxin-like 4B) or DLP, is a 149-amino acid nuclear protein that exists as a homodimer and plays an essential role in pre-mRNA splicing. It shares 38% sequence identity with Dim1 and is required for S/G₂ transition during the cell cycle. Dim2 binds the PRP6 (U5-102K) subunit of the spliceosome.
The gene encoding Dim2 maps to human chromosome 16, which encodes over 900 genes (~3% of the human genome). Disorders associated with chromosome 16 include Rubinstein-Taybi syndrome and Crohn’s disease.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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