Thermo Fisher Scientific Periplakin/PPL Polyclonal Antibody
Rabbit polyclonal antibody against human Periplakin (PPL). Validated for WB and IP applications. Targets residues 1150–1200. Supplied as liquid, 0.2 mg/mL concentration. Recommended storage at 4°C for 1 year.
- 판매단위
- pk
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000–1:10,000 |
| Immunoprecipitation (IP) | 2–5 µg/mg lysate |
Product Specifications
| Property | Description |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 1150 and 1200 of human periplakin |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.20 mg/mL |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
The recommended shelf life for this product is 1 year from the date of receipt.
Target Information
The protein encoded by this gene is a component of desmosomes and the epidermal cornified envelope in keratinocytes. The N-terminal domain interacts with the plasma membrane, while the C-terminus binds intermediate filaments. Through its rod domain, this protein forms complexes with envoplakin, linking the cornified envelope and desmosomes. AKT1/PKB, a protein kinase involved in cell growth and survival signaling, is reported to interact with this protein, suggesting a potential role as a localization signal in AKT1-mediated signaling.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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