Thermo Fisher Scientific PRDX5 Monoclonal Antibody (OTI3A1), TrueMAB
PRDX5 단백질을 인식하는 마우스 단클론 항체로 Western blot 및 IHC(파라핀 절편)에 사용 가능. HEK293T 세포에서 발현된 인간 PRDX5 전장 단백질로 면역화됨. 1 mg/mL 액상 형태, PBS/BSA/glycerol buffer에 보존. 연구용으로만 사용.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:150 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI3A1 |
| Immunogen | Full length human recombinant protein of human PRDX5 produced in HEK293T cells. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Peroxiredoxin (Prx) is a growing peroxidase family associated with cell proliferation, differentiation, and apoptosis. Mammalian Prx proteins (about 50 isoforms) share active site cysteine residues and thiol-specific antioxidant activity. Six mammalian members are classified as typical 2-Cys, atypical 2-Cys, and 1-Cys Prx. Except for Prx VI (1-Cys subgroup), the other five 2-Cys Prx types function as thioredoxin-dependent peroxidases (TPx), utilizing thioredoxin, thioredoxin reductase, and NADPH as reducing systems. Mammalian Prxs are 20–30 kDa proteins with diverse subcellular localization: Prx I, II, and VI in cytosol; Prx III in mitochondria; Prx IV in ER and secretion; and Prx V in peroxisome, mitochondria, and cytosol.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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