Thermo Fisher Scientific LRFN1 Polyclonal Antibody
LRFN1 단백질을 인식하는 Thermo Fisher Scientific의 폴리클로날 항체로, 인간·마우스·랫에서 반응합니다. IHC, ICC/IF, ELISA 등 다양한 응용에 사용 가능하며, 고순도 Protein A 정제 및 안정한 액상 형태로 제공됩니다. 연구용으로만 사용됩니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:500 |
| Immunohistochemistry (Frozen) (IHC (F)) | 1:100–1:500 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
| ELISA | 1:500–1:1,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic peptide derived from human LRFN1, amino acids 181–290 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
LRFN1 is one of a family of five transmembrane glycoproteins highly expressed in neuronal tissues. These proteins share a leucine-rich repeat (LRR)-immunoglobulin-like (Ig)-fibronectin type III (Fn)-transmembrane domain structure, similar to the Slitrk family. Expression of LRFN1, -3, and -4 mRNA has been detected in embryonic neuronal cells, while Lrfn2 and Lrfn5 are mainly expressed in mature cells. LRFN1, -2, and -4 bind to PDZ domains of postsynaptic PSD95, redistributing PSD95 to the cell periphery. Lrfn proteins are suggested to play roles in the developing and/or mature vertebrate nervous system. At least two isoforms of LRFN1 are known to exist.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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