
Thermo Fisher Scientific IL-18 Recombinant Mouse Monoclonal Antibody (125-2H)
인간 IL-18 활성형을 인식하는 마우스 단클론 항체입니다. 다양한 응용(ICC/IF, ELISA, IP, Neutralization)에 사용 가능합니다. HEK293 세포에서 발현된 recombinant 형태로, Protein A로 정제되었습니다. 연구용으로만 사용 가능합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunocytochemistry (ICC/IF) | Assay-dependent |
| ELISA | Assay-dependent |
| Immunoprecipitation (IP) | Assay-dependent |
| Neutralization (Neu) | Assay-dependent |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1, kappa |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 125-2H |
| Immunogen | Fusion of splenocytes from mice immunized with human IL-18, with SP2/O mouse myeloma cells |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_3074242 |
Product Specific Information
Specificity: Recognizes the active form of human IL-18.
Target Information
The protein encoded by this gene is a proinflammatory cytokine that induces IFN-gamma production in T cells.
In combination with IL-12, it inhibits IL-4 dependent IgE and IgG1 production while enhancing IgG2a production in B cells.
IL-18 binding protein can specifically interact with this cytokine to negatively regulate its biological activity.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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