Thermo Fisher Scientific FUZ Polyclonal Antibody
FUZ 단백질을 인식하는 Rabbit Polyclonal Antibody로, Western blot 및 IHC(P)에서 검증됨. Human, Mouse, Rat 등 다양한 종에 반응. Protein G 정제, 0.5 mg/mL 농도. PBS + BSA buffer, -20°C 보관.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 2–6 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 15 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Non-human primate, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide corresponding to amino acids 338–382 of human FUZ |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Protein G |
| Storage Buffer | PBS with 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2540735 |
Target Information
FUZ is the human homolog of the Drosophila fy protein and belongs to the fuzzy family. The fy gene of Drosophila encodes a novel four-pass transmembrane protein that plays two roles in the development of hairs on the Drosophila wing:
- Specifies correct orientation of the hair by restricting its initiation to the distal vertex of the cell.
- Permits development of a single cell hair by maintaining the integrity of F-actin and microtubule arrays required for hair formation.
In humans, FUZ is involved in cytoskeleton function and cell polarity in epithelial cells. The human fuz gene is localized on chromosome 19q13.33.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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