Thermo Fisher Scientific CXCL13 Polyclonal Antibody
Canine CXCL13/BCA-1 특이성을 가진 Rabbit Polyclonal Antibody로 ELISA에 적합. 보존제가 없는 액상 형태이며, 단백질 A 및 항원 친화 크로마토그래피로 정제됨. 장기 보관은 -20°C에서 권장. 연구용으로만 사용 가능.
- 카탈로그번호
- PA580276
- 판매단위
- pk
카탈로그
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Applications
ELISA (ELISA)
- Tested Dilution: 1:5,000–1:10,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Dog |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant Canine BCA-1/CXCL13 protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A, Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2787607 |
Product Specific Information
This product is preservative-free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%–0.1%).
This antibody has specificity for Canine BCA-1/CXCL13.
Target Information
CXCL13, also known as BCA-1 and Angie, is a small chemokine strongly expressed in secondary lymphoid organs. It promotes migration of B lymphocytes (B-1 and B-2) to follicles of the spleen, lymph nodes, and Peyer’s patches.
Produced by macrophages, with high expression in large peritoneal macrophages, Kupffer cells, and lung macrophages (CD11c+ and CD11c−).
The cellular ligand for CXCL13 is CXCR5 (BLR-1), expressed on B cells, Tfh cells, and some memory T cell populations.
CXCL13 is involved in chronic lymphocytic leukemia (CCL) development and serves as a plasma biomarker for germinal center activity and broadly neutralizing antibody generation against HIV.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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