Thermo Fisher Scientific MICALL2 Polyclonal Antibody

Applications

Tested Dilution

Publications

Immunohistochemistry (Paraffin) (IHC (P))

1:200-1:500

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human MICALL2. Recombinant protein control fragment (Product #RP-92856). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:MICALL2,uniProtId:Q8IY33-1,ncbiNodeId:9606,antigenRange:674-765,antigenLength:904,antigenImageFileName:PA5-55240_MICALL2_Q8IY33-1_Rabbit.svg,antigenImageFileNamePDP:PA5-55240_MICALL2_Q8IY33-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1.1 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2643960

Product Specific Information

Immunogen sequence: DVCDNWLRPE PPGQEARVQS WKEEEKKPHL QGKPGRPLSP ANVPALPGET VTSPVRLHPD YLSPEEIQRQ LQDIERRLDA LELRGVELEK RL

Highest antigen sequence identity to the following orthologs: Mouse - 59%, Rat - 57%.

Target Information

Effector of small Rab GTPases which is involved in junctional complexes assembly through the regulation of cell adhesion molecules transport to the plasma membrane and actin cytoskeleton reorganization. Regulates the endocytic recycling of occludins, claudins and E-cadherin to the plasma membrane and may thereby regulate the establishment of tight junctions and adherens junctions. In parallel, may regulate actin cytoskeleton reorganization directly through interaction with F-actin or indirectly through actinins and filamins. Most probably involved in the processes of epithelial cell differentiation, cell spreading and neurite outgrowth. [UniProt]

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.