Thermo Fisher Scientific MICALL2 Polyclonal Antibody
Human MICALL2 단백질을 인식하는 Rabbit Polyclonal Antibody로, IHC(P) 실험에 적합합니다. 항원 친화 크로마토그래피로 정제되었으며, PBS 및 40% glycerol buffer에 보관됩니다. 세포 접착 및 junction 조절 연구에 활용 가능합니다.
- 카탈로그번호
- PA555240
- 판매단위
- pk
카탈로그
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Thermo Fisher Scientific MICALL2 Polyclonal Antibody
Applications
- Immunohistochemistry (Paraffin) (IHC (P)): 1:200–1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human MICALL2. Recombinant protein control fragment (Product #RP-92856). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2643960 |
Product Specific Information
Immunogen sequence:
DVCDNWLRPE PPGQEARVQS WKEEEKKPHL QGKPGRPLSP ANVPALPGET VTSPVRLHPD YLSPEEIQRQ LQDIERRLDA LELRGVELEK RL
Highest antigen sequence identity to the following orthologs:
- Mouse: 59%
- Rat: 57%
Target Information
Effector of small Rab GTPases involved in junctional complex assembly through regulation of cell adhesion molecule transport to the plasma membrane and actin cytoskeleton reorganization. Regulates endocytic recycling of occludins, claudins, and E-cadherin to the plasma membrane, thereby influencing tight and adherens junction formation. Also participates in actin cytoskeleton reorganization directly via F-actin interaction or indirectly via actinins and filamins. Likely involved in epithelial cell differentiation, cell spreading, and neurite outgrowth. [UniProt]
Usage Note
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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