Thermo Fisher Scientific TRIB2 Polyclonal Antibody
TRIB2 단백질을 인식하는 Rabbit Polyclonal 항체로, Human, Mouse, Rat 시료에 반응합니다. Western Blot 및 IHC(P) 분석에 적합하며, 항원 친화 크로마토그래피로 정제되었습니다. 동결건조 형태로 제공되며 재구성 후 500 µg/mL 농도로 사용 가능합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.1–0.5 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 0.5–1 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide corresponding to a sequence in the middle region of human TRIB2 (175–211aa DLKLRKFIFKDEERTRVKLESLEDAYILRGDDDSLSD). |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 500 µg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS with 5 mg BSA |
| Contains | 0.05 mg sodium azide |
| Storage Conditions | –20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2747300 |
Product Specific Information
Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 µg/mL.
Target Information
The TRIB2 gene encodes one of three members of the Tribbles family. These proteins share a Trb domain homologous to protein serine-threonine kinases but lack the active site lysine, likely resulting in no catalytic function. Tribbles proteins interact with and modulate signal transduction pathways involved in various physiological and pathological processes. This member induces apoptosis primarily in hematopoietic cells and is upregulated by inflammatory stimuli in myeloid (THP-1) cells. It also acts as an oncogene that inactivates the transcription factor C/EBPalpha, contributing to acute myelogenous leukemia. Alternatively spliced transcript variants have been identified for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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