Thermo Fisher Scientific DCX Monoclonal Antibody (OTI4A3), TrueMAB
인간 DCX 단백질을 인식하는 마우스 단일클론 항체로, Western blot, ICC/IF, Flow cytometry에 적합합니다. 고순도 친화 크로마토그래피 정제, 동결건조 형태로 제공되며 PBS 기반 버퍼에 보존제 무첨가. 연구용으로 신경세포 이동 관련 단백질 분석에 유용.
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Thermo Fisher Scientific DCX Monoclonal Antibody (OTI4A3), TrueMAB
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
| Immunocytochemistry (ICC/IF) | 1:100 |
| Flow Cytometry (Flow) | 1:100 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI4A3 |
| Immunogen | Full length human recombinant protein of human DCX produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments using this carrier-free antibody, perform an additional round of desalting (Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
DCX (Doublecortin) is a cytoplasmic protein that regulates neuronal migration by organizing and stabilizing microtubules in the developing cortex. It contains two doublecortin domains that bind microtubules and interacts with LIS1, a regulatory subunit of platelet activating factor acetylhydrolase. This interaction is critical for proper microtubule function. Mutations in the DCX gene cause X-linked lissencephaly.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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