Thermo Fisher Scientific GABARAP Polyclonal Antibody
GABARAP 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot과 IHC(P)에서 검증됨. 인간, 마우스, 랫트 반응성. 동결건조 형태로 제공되며, 재구성 후 사용 가능. GABA 수용체 관련 연구 및 자가포식 경로 연구에 적합.
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Applications and Tested Dilutions
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:100–1:2,000 | – |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200 | – |
| Miscellaneous PubMed (Misc) | – | View 2 publications |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Published species | Not Applicable |
| Host / Isotype | Rabbit / Ig |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide from the N-terminal region of human GABARAP conjugated to an immunogenic carrier protein |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | Not determined |
| Storage buffer | Whole serum |
| Contains | No preservative |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for added stability. |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Reconstitute in 150 µL of sterile water.
- Centrifuge to remove any insoluble material.
- Specificity: GABARAP.
Target Information
Gamma-aminobutyric acid (GABA) is the main inhibitory neurotransmitter in the central nervous system, increasing Cl⁻ conductance to inhibit neuronal firing. It activates ionotropic (GABAA) and metabotropic (GABAB) receptors, as well as GABAC receptors.
GABARAP (GABAA receptor-associated protein) links GABAA receptors to the cytoskeleton and may play a role in intracellular transport and receptor-cytoskeleton interaction.
GABARAP belongs to the MAP1/ATG8-like family, and studies indicate that MAPK15/ERK8 interacts with ATG8 family proteins to regulate autophagy.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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