Thermo Fisher Scientific MMP12 Polyclonal Antibody
Human MMP12 단백질을 인식하는 Rabbit Polyclonal Antibody로, WB 및 IHC(P) 실험에 적합. 항원 친화 크로마토그래피로 정제된 고품질 항체이며, 비결합형 액상 형태로 제공. 연구용으로만 사용 가능.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:3,000
- Publications: []
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:100–1:1,000
- Publications: []
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fragment corresponding to amino acids 203–441 of Human MMP12 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | 0.1M Tris glycine, pH 7, with 10% glycerol |
| Contains | 0.01% thimerosal |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2545294 |
Product Specific Information
- Recommended positive controls: 293T
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
Matrix metalloproteinase (MMP) family proteins are involved in extracellular matrix breakdown in normal processes such as embryonic development, reproduction, and tissue remodeling, as well as in diseases like arthritis and metastasis. Most MMPs are secreted as inactive proproteins activated by extracellular proteinases. The MMP12 enzyme degrades soluble and insoluble elastin and may play a role in aneurysm formation and emphysema development. The MMP12 gene localizes to chromosome 11q22.3.
⚠ WARNING: This product can expose you to chemicals including mercury, known to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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