Thermo Fisher Scientific TMSB4X Polyclonal Antibody
TMSB4X 단백질을 인식하는 Rabbit Polyclonal 항체로, 인간, 마우스, 랫트 시료에 반응합니다. IHC(P)에서 1:25~1:100 희석으로 사용 가능하며, 액상 형태로 제공됩니다. 항원 친화 크로마토그래피로 정제되었으며, -20°C에서 보관합니다.
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:25–1:100
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to residues near the N-terminal of human thymosin beta 4, X-linked |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 40% glycerol |
| Contains | 0.05% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2636037 |
Product Specific Information
This antibody detects endogenous levels of total Thymosin beta 4 protein.
Target Information
Thymosin-beta4 is a small, actin-sequestering protein belonging to the thymosin-beta family. It is found at high concentrations in the spleen, thymus, and peritoneal macrophages, where it plays a key role in cytoskeletal organization. In mammalian tissues, it modulates actin polymerization and depolymerization by forming a 1:1 complex with G-actin, preventing its polymerization into F-actin. Thymosin-beta4 is abundant in the brain, lungs, liver, kidneys, testes, and heart, and is also synthesized by myoblasts and fibroblasts. It is expressed irregularly in several hematopoietic and malignant cell lines. Additionally, it has been shown to regulate hormone secretion, macrophage migration, T cell differentiation, and stem cell cycle progression.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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