Thermo Fisher Scientific Livin Polyclonal Antibody
Thermo Fisher Scientific의 Livin Polyclonal Antibody는 인간 Livin 단백질을 타깃으로 하는 토끼 유래 다클론 항체입니다. Western blot에 적합하며, 항원 친화 크로마토그래피로 정제되었습니다. 4°C 단기 보관, -20°C 장기 보관 권장. 연구용으로만 사용됩니다.
- 카탈로그번호
- PA131123
- 판매단위
- pk
카탈로그
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide GPQPSHWAAGDGPTQERC, corresponding to N-terminal amino acids 13–30 of Human Livin |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_1956634 |
Product Specific Information
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
The inhibitor of apoptosis (IAP) family of proteins regulates programmed cell death triggered by various stimuli. All IAPs have at least one baculovirus IAP repeat (BIR) motif essential for their anti-apoptotic activity.
Livin (also known as ML-IAP) is a human IAP family member containing a single BIR domain and a COOH-terminal RING finger domain. The Livin gene has two splicing variants encoding proteins of 298 and 280 amino acids, both containing BIR and RING domains. Both isoforms inhibit TNFα-induced apoptosis in Jurkat cells. Livin expression is low in adult tissues but relatively higher in developmental tissues and many cancer cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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