Thermo Fisher Scientific Cytokeratin 1 Polyclonal Antibody
사이토케라틴 1 단백질을 인식하는 토끼 폴리클로날 항체로, Western blot, IHC, Flow cytometry에 사용 가능. 인간 시료에 반응하며 비결합형 액상 형태로 제공. 연구용으로 세포 분화 및 상피 종양 구분 연구에 적합.
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Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:1,000 | View 1 publication |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:100 | - |
| Flow Cytometry (Flow) | 1:10–1:50 | - |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Published Species | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic peptide between 415–443 amino acids from the central region of human KRT1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 2 mg/mL |
| Purification | Size-exclusion, Dialysis, Ammonium sulfate precipitation |
| Storage Buffer | PBS, pH 7.4 |
| Contains | 0.09% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2544199 |
Target Information
Cytokeratins are a subfamily of intermediate filament proteins exhibiting remarkable biochemical diversity, represented in human epithelial tissues by at least 20 different polypeptides. They range in molecular weight between approximately 40 kDa and 68 kDa, and isoelectric pH between 4.9 and 7.8.
Each cytokeratin (numbered 1–20) is characteristic of specific epithelial types and their differentiation stages. Cytokeratin subtype expression patterns are widely used in distinguishing epithelial malignancies.
Cytokeratin antibodies are valuable tools in differential tumor diagnosis using immunohistochemistry, as well as in cytopathology and flow cytometric assays.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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